Endocrine Abstracts

Introduction: Adrenocortical carcinoma (ACC) is a rare malignant tumor with heterogeneous prognosis. The median overall survival of all ACC patients is about 3-4 years. Complete surgical resection provides the only cure [Fassnacht M, et al., 2018]. In cases of advanced ACC, therapeutic options are limited. No effective second-line therapies are recommended for patients with disease progression to EDP chemotherapy scheme and Mitotane. It is essential to study alternative drugs,...

Growth hormone (GH) producing tumors are commonly associated with menstrual disorders and anovulation because of the direct effects of tumor mass on gonadotropins and possible association with hyperprolactinemia. However, some women with acromegaly get pregnant, which rises up a lot of questions about medication, complications and follow-up. We report outcomes of 7 cases of pregnancy in patients with active acromegaly. A median age of patients was 30 years, four of them were w...